Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis.
Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis.
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DOI：
10.4081/ejtm.2014.3790
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发表时间：
2014-09-23
影响因子：
2.2
通讯作者：
Adamo S
中科院分区：
文献类型：
--
作者：
Costa A;Rossi E;Scicchitano BM;Coletti D;Moresi V;Adamo S
自20世纪80年代S以来，神经垂体激素血管加压素和催产素出现了新的功能作用。一些研究已经调查了这两种神经激素在体外和体内对横纹肌组织的影响。加压素对骨骼肌源性细胞、发育中的肌肉和肌肉内稳态的影响已有文献记载。催产素似乎对心肌分化和心脏动态平衡有更大的影响。本文综述了这两种神经垂体激素的新作用，并为影响横纹肌的疾病开辟了新的治疗途径。
Since the 1980’s, novel functional roles of the neurohypophyseal hormones vasopressin and oxytocin have emerged. Several studies have investigated the effects of these two neurohormones on striated muscle tissues, both in vitro and in vivo. The effects of vasopressin on skeletal myogenic cells, developing muscle and muscle homeostasis have been documented. Oxytocin appears to have a greater influence on cardiomyocite differentiation and heart homeostasis. This review summarizes the studies on these novel roles of the two neurohypophyseal hormones, and open the possibility of new therapeutic approaches for diseases affecting striated muscle.