CASE-CONTROL STUDY OF LUNG-CANCER AND TRUCK DRIVING IN THE TEAMSTERS-UNION
CASE-CONTROL STUDY OF LUNG-CANCER AND TRUCK DRIVING IN THE TEAMSTERS-UNION
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DOI：
10.2105/ajph.80.6.670
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发表时间：
1990-06-01
影响因子：
12.7
通讯作者：
HORNUNG, RW
中科院分区：
文献类型：
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作者：
STEENLAND, NK;SILVERMAN, DT;HORNUNG, RW
我们在卡车司机工会进行了一项肺癌死亡病例对照研究，在控制吸烟和其他混杂因素后，比较卡车司机中不同职业的风险。无柴油机烟雾暴露的职业者为非暴露组。研究人群包括996名病例和1,085名对照，他们在1982-83年申请养老金后死亡。近亲提供了吸烟、工作史和其他潜在混杂因素的信息。 工作历史数据也从卡车司机工会获得。虽然没有一个单一的工作类别与未接触组相比有显著的超额风险，但某些亚组的风险有所升高。1959年（柴油发动机引进的大致日期）后长期从事长途卡车司机工作的人的优势比为1.55（95%CI：0.97，2.47）。长期驾驶柴油卡车的人的优势比为1.89（95% CI：1.04，3.42）。总的来说，我们的研究结果表明，与卡车运输行业以外的其他卡车司机相比，柴油卡车司机患肺癌的风险过高。然而，我们的研究结果并不一致，我们的数据有许多局限性，其中最重要的是缺乏接触柴油烟雾的数据。
We conducted a case-control study of lung cancer deaths in the Teamsters Union to compare the risk of different occupations within the teamsters, after controlling for smoking and other confounders. Occupations with no presumed expsoure to diesel fumes were used as the nonexposed group. The study population consisted of 996 cases and 1,085 controls who had died in 1982-83 after applying for pensions. Next of kin provided information on smoking, work history, and other potential confounders. Work history data were also obtained from the Teamsters Union. While no single job category had a significant excess risk compared to the non-exposed group, certain sub-groups were elevated. The odds ratio for those with long-term employment as long-haul truckers after 1959 (an approximate date for the introduction of diesel engines) was 1.55 (95% CI: 0.97, 2.47). Long-term drivers of primarily diesel trucks had an odds ratio of 1.89 (95% CI: 1.04, 3.42). Overall, our results suggest that diesel truck drivers have an excess risk of lung cancer compared to other teamsters in jobs outside the trucking industry. However, our findings were not uniformly consistent and our data have many limitations, the most important of which is the lack of data on exposure to diesel fumes.