Critical review of liability for benzodiazepine abuse among alcoholics.
Critical review of liability for benzodiazepine abuse among alcoholics.
复制标题
对酗酒者滥用苯二氮卓类药物责任的严格审查。
DOI：
10.1176/ajp.145.12.1501
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Shader,RI
中科院分区：
文献类型：
--
作者：
Ciraulo,DA;Sands,BF;Shader,RI
作者批判性地回顾了关于酗酒者、精神病患者和普通人群使用苯二氮卓类药物的文献，以确定酗酒者是否对苯二氮卓类药物滥用有更大的责任。数据表明，酗酒者中苯二氮卓类药物的使用率高于一般人群，但与精神病患者中的患病率相当。对于酗酒者来说，滥用的责任也可能更大，但现有研究的方法学上的重大缺陷排除了这样的结论。鉴于酗酒者中焦虑症和苯二氮卓类药物使用的频率，他们滥用苯二氮卓类药物的可能性是一个重要问题。作者讨论了未来研究的临床指南和策略。
The authors critically reviewed the literature on benzodiazepine use among alcoholics, psychiatric patients, and the general population to determine whether alcoholics have a greater liability for benzodiazepine abuse. Data suggest that the prevalence of benzodiazepine use among alcoholics is greater than in the general population but comparable to the prevalence in psychiatric patients. The liability for abuse may also be greater for alcoholics, but the substantial methodologic deficiencies of existing studies preclude such a conclusion. Given the frequency of anxiety disorders and benzodiazepine use among alcoholics, their potential for benzodiazepine abuse is an important issue. The authors discuss clinical guidelines and strategies for future research.