Regulation of cytochrome P450 activity by physicochemical methods

Regulation of cytochrome P450 activity by physicochemical methods
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物理化学方法调控细胞色素P450活性

DOI:
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发表时间:
2000
期刊:
影响因子:
--
通讯作者:
A. Archakov
A. Archakov
中科院分区:
--
文献类型:
--
作者:
V. V. Shumyantseva;T. Bulko;A. Archakov

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Physicochemical factors influencing the catalytic activities of hemoproteins (of cytochrome P450, in particular) that find use in biosensors and bioreactors are considered. The authors' data on the preparation of semisynthetic hemoproteins based on cytochrome P450 2B4 and NADPH-dependent cytochrome P450 reductase are presented. The use of alternative electron sources (electrochemical reduction and photoreduction) for the redox cycle of hemoproteins is discussed. The effects of temperature, pressure, chemical modification of proteins and organic solvents on the efficiency of hemoprotein- catalysed enzymic reactions are analysed. The bibliography includes 86 references.
完全还原酶的单电子光氧化作用下酵母黄细胞色素 b2 的分子内电子转移:血红素-黄素通讯氧化还原状态控制的证据。
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DOI: --
发表时间: 2004
期刊: Biochemistry 43
影响因子: --
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通讯作者: et al.