Eicosapentaenoic Acid-Rich Fish Oil Supplementation Inhibits the Decrease in Concentric Work Output and Muscle Swelling of the Elbow Flexors
Eicosapentaenoic Acid-Rich Fish Oil Supplementation Inhibits the Decrease in Concentric Work Output and Muscle Swelling of the Elbow Flexors
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DOI：
10.1080/07315724.2018.1470042
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发表时间：
2019-02-17
影响因子：
3.5
通讯作者：
Tsuchiya, Yosuke
中科院分区：
文献类型：
--
作者：
Ochi, Eisuke;Yanagimoto, Kenichi;Tsuchiya, Yosuke
目的：本研究的目的是检验这样的假设：补充 8 周二十碳五烯酸 (EPA) 和二十二碳六烯酸 (DHA) 通过人类肘屈肌的同心收缩 (CON) 改善外周肌肉性能。方法：通过双盲法，对 16 名健康男性随机服用 EPA 和 DHA 补充剂（EPA，n = 8）或安慰剂（PL，n = 8）。 EPA 组每天服用富含 EPA 的鱼油，其中含有 600 毫克 EPA 和 260 毫克 DHA，持续 8 周。受试者进行了 5 组，每组 6 次肘屈肌最大 CON。在运动期间评估工作输出和峰值扭矩。还评估了运动前、运动后立即和运动后 1 天的最大自愿等长收缩扭矩、运动范围 (ROM)、上臂周长、通过感知用力评级的肌肉疲劳、横向松弛时间、横截面积 (CSA) 和血液中的乳酸。结果：第五组 EPA 组 CON 期间的工作输出高于安慰剂组（EPA 组；94.0 +/- 11.7%，安慰剂组；82.5 +/- 11.7%，p < 0.05）。此外，运动后 EPA 组的 ROM 显着高于安慰剂组 (p < 0.05)。运动后，EPA 组 CSA 的增加明显小于安慰剂组 (p < 0.05)。结论：本研究表明，补充 8 周的 EPA 和 DHA 可以减轻 30 CON 引起的肌肉做功减少。此外，补充EPA和DHA可以抑制CON后ROM的减少和CSA的增加。
Objective: The aim of this study was to test the hypothesis that 8-week eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation improves peripheral muscle performance by concentric contractions (CONs) of elbow flexors in humans. Methods: Sixteen healthy men were randomly administered with EPA and DHA supplement (EPA, n = 8) or placebo (PL, n = 8) by a double-blind method. The EPA group was administered EPA-rich fish oil, containing 600 mg EPA and 260 mg DHA per day for 8 weeks. The subjects performed 5 sets of 6 maximal CONs of elbow flexors. The work output and peak torque were assessed during exercise. Changes in the maximal voluntary isometric contraction torque, range of motion (ROM), upper arm circumference, muscle fatigue by rating of perceived exertion, transverse relaxation time, cross-sectional area (CSA), and lactate in blood were also assessed before, immediately after, and 1 day after exercise. Results: The work output during CONs in the EPA group was greater than that in the placebo group at the fifth set (EPA group; 94.0 +/- 11.7%, placebo group; 82.5 +/- 11.7%, p < 0.05). In addition, ROM in the EPA group was significantly greater than that in the placebo group immediately after exercise (p < 0.05). The increase of CSA in the EPA group was significantly smaller than that in the placebo group immediately after exercise (p < 0.05). Conclusions: The present study suggests that the reduction of muscle work output caused by 30 CONs can be attenuated by an 8-week EPA and DHA supplementation. In addition, EPA and DHA supplementation can cause inhibition for reduction of ROM and increase of CSA after CONs.