Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus
Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus
复制标题
桉树 A-C 具有从蓝桉中分离出的新骨架
DOI：
10.1021/ol7025075
复制
发表时间：
2007-12-20
期刊：
影响因子：
5.2
通讯作者：
Yue, Jian-Min
中科院分区：
文献类型：
--
作者：
Yin, Sheng;Xue, Jun-Juan;Yue, Jian-Min
从蓝桉（Eucalyptus globulus）果实中分离得到一个新骨架为3，5-二甲酰基-异戊基间苯三酚偶联杜松烷（cadinane）的桉树醛（Eucalyptal A-C（1-3））。化合物1的结构经X-射线单晶衍射证实。还推测了1-3的生物合成途径。化合物1-3对HL-60细胞系表现出选择性细胞毒性。
Eucalyptals A-C (1-3) with a new skeleton of 3,5-diformyl-isopentyl phloroglucinol-coupled cadinane were isolated from the fruits of Eucalyptus globulus. Their structures were elucidated by spectroscopic analysis, and that of 1 was confirmed by single-crystal X-ray diffraction. The biosynthetic pathway of 1-3 was also postulated. Compounds 1-3 exhibited selective cytotoxicity against the HL-60 cell line.