Beagle dog pulmonary surfactant lipids. Lipid composition of pulmonary tissue, exfoliated lining cells and surfactant.
Beagle dog pulmonary surfactant lipids. Lipid composition of pulmonary tissue, exfoliated lining cells and surfactant.
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比格犬肺表面活性物质脂质。
DOI：
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发表时间：
1971
影响因子：
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通讯作者：
H. G. Thomas
中科院分区：
文献类型：
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作者：
R. Pfleger;H. G. Thomas
正常比格犬肺、肺表面活性物质和脱落衬里细胞的脂质通过既定程序定量。通过支气管内盐水灌洗获得表面活性剂和细胞。磷脂占表面活性剂和细胞脂质的70%以上：磷脂酰胆碱是主要的磷脂。磷脂酰甘油存在于比格犬肺表面活性物质（磷脂-P的10%）、脱落衬里细胞（磷脂-P的7%）和肺组织（磷脂-P的3%）中。胆固醇及其酯类占中性脂质组分的60%以上。对所有样品中性脂质和磷脂中的烷基和1-烯基甘油醚进行定量。
The lipids from normal beagle dog lungs, pulmonary surfactant, and exfoliated lining cells were quantitated by established procedures. The surfactant and cells were obtained by endobronchial saline lavage. Phospholipids accounted for more than 70% of the surfactant and cell lipids: phosphatidyl choline was the predominant phosphatide. Phosphatidyl glycerol is present in beagle dog pulmonary surfactant (10% of phospholipid-P), exfoliated lining cells (7% of phospholipid-P) and lung tissue (3% of phospholipid-P). Cholesterol and its esters accounted for more than 60% of the neutral lipid fractions. Alkyl and alk-1-enyl glycerol ethers were quantitated in the neutral lipids and phospholipids from all samples.