Assessing a sustainable manufacturing route to lapatinib

Assessing a sustainable manufacturing route to lapatinib
复制标题

评估拉帕替尼的可持续生产路线

DOI:
10.1039/d2re00267a
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发表时间:
2022
影响因子:
3.9
通讯作者:
Stark R
Stark R
中科院分区:
化学2区
文献类型:
--
作者:
Stark R

文献摘要

相似文献

设计了一种抗癌药物拉帕替尼的合成路线,以支持南非可持续制造工艺的发展。采用定量指标来评价反应关键步骤的可持续性。
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction.