STIMULUS SELECTIVITY AND STATE DEPENDENCE OF ACTIVITY IN INFERIOR TEMPORAL CORTEX OF INFANT MONKEYS
STIMULUS SELECTIVITY AND STATE DEPENDENCE OF ACTIVITY IN INFERIOR TEMPORAL CORTEX OF INFANT MONKEYS
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DOI：
10.1073/pnas.88.17.7572
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发表时间：
1991-09-01
影响因子：
11.1
通讯作者：
GROSS, CG
中科院分区：
文献类型：
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作者：
RODMAN, HR;SKELLY, JP;GROSS, CG
下颞叶皮层是成年灵长类动物视觉物体识别所必需的，但在婴儿中不那么重要。尽管如此，在6周龄的猕猴中，下颞神经元表现出类似成年人的视觉反应特性，包括形式选择性和双侧感受野，这表明延长的成熟和视觉体验可能不是复杂物体的成人编码所必需的。然而，在动物4个月大之前，只在清醒的猴子执行行为任务时在下颞叶皮层发现了视觉反应，而在麻醉的猴子中没有发现，这表明视网膜外因素深刻地影响了发育中和成熟动物的“联合”皮层的功能。
Inferior temporal cortex is necessary for visual object recognition in adult primates but is less critical in infants. Nonetheless, in macaques as young as 6 weeks old, inferior temporal neurons showed adult-like visual response properties, including form selectivity and bilateral receptive fields, indicating that extended maturation and visual experience may not be necessary for adult-like encoding of complex objects. However, before the animals were 4 months old, visual responsiveness was found in inferior temporal cortex only in awake monkeys performing a behavioral task and not in anesthetized ones, suggesting that extraretinal factors profoundly influence function in "association" cortex in developing as well as mature animals.