THERMAL CATARACT FORMATION IN RABBITS

THERMAL CATARACT FORMATION IN RABBITS
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DOI:
10.1002/bem.2250080408
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发表时间:
1987-01-01
影响因子:
1.9
通讯作者:
GUY, AW
GUY, AW
中科院分区:
生物学4区
文献类型:
--
作者:
KRAMAR, P;HARRIS, C;GUY, AW

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用眼内循环热水维持晶状体后温度在43℃以下,造成7只兔9只眼白内障。C和45度。C.快速升温(1.3度。C/分钟),加上眼睛上的急剧温度梯度,可能是在这种温度下持续产生白内障的因素。生物显微镜和光学显微镜显示晶状体的变化与急性暴露在微波辐射下的变化相似。这些发现支持这样一种假设,即微波白内障是由于局部温度升高造成的。
Intraocularly circulating hot water was used to produce cataracts in nine eyes of seven rabbits by maintaining their retrolental temperatures between 43.degree. C and 45.degree. C. A rapid rate of heating (1.3.degree. C/min) plus a sharp temperature gradient across the eye may have been contributing factors in the consistent production of cataracts at these temperatures. Biomicroscopy and light microscopy showed lens changes similar to those associated with acute exposure to microwave radiation. These findings support the assumption that microwave cataractogenesis is due to the local production of elevated temperatures.