Burkitt lymphoma in a child with human immunodeficiency virus infection.
Burkitt lymphoma in a child with human immunodeficiency virus infection.
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患有人类免疫缺陷病毒感染的儿童患有伯基特淋巴瘤。
DOI：
10.1016/s0022-3476(88)80062-3
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Brandsma,J
中科院分区：
文献类型：
--
作者：
Kamani,N;Kennedy,J;Brandsma,J
方法病例报告.一个4岁的黑人男孩，足月出生的静脉药物滥用的母亲，被送往医院的发烧，腹痛，呕吐，厌食，腹围增加几天的历史。他一直很好，直到2岁，当全身淋巴结病，肝肿大，并未能茁壮成长，在住院期间被认为是病毒性肺炎。当时的免疫学研究显示多克隆高丙种球蛋白血症、逆转的辅助（T4）与抑制（T8）T细胞比率和HIV抗体血清阳性。除了由于另一次假定的病毒性肺炎发作而短暂住院外，他在本次入院前显然一直很好。体格检查发现一名无发热、营养不良的儿童，体重为第5百分位数，身高低于第5百分位数。他有巩膜黄疸和全身淋巴结病，淋巴结直径为0.5 - 1.0 cm。他的腹部隆起，有些触痛。在右肋缘下8 cm处可触及肝脏，跨度为11 cm。脾脏未触及。
METHODSCase Report. A 4-year-old black male child, born at term to an intravenous drug abusing mother, was admitted to the hospital with a several-day history of fever, abdominal pain, vomiting, anorexia, and increasing abdominal girth. He had been well until age 2 years, when generalized lymphadenopathy, hepatomcgaly, and failure to thrive were noted during a hospitalization for presumed viral pneumonia. Immunologic studies at the time revealed polyclonal hypergammaglobulinemia, reversed helper (T4) to suppressor (T8) T cell ratio, and seropositivity for antibodies to HIV. Except for a brief hospitalization because of another episode of presumed viral pneumonia, he remained apparently well until the current admission. Physical examination revealed an afebrile, undernourished child with weight at the 5th percentile and height below the 5th percentile for age. He had scleral icterus and generalized lymphadenopathy, with lymph nodes 0.5 to 1.0 cm in diameter. His abdomen was protuberant and somewhat tender. The liver was palpable 8 cm below the right costal margin, with a span of 11 cm. The spleen was not palpable.