Radioimmunoassay for thymopoietin.
Radioimmunoassay for thymopoietin.
复制标题
胸腺生成素的放射免疫测定。
作者：
G. Goldstein
开发了胸腺生成素的放射免疫测定法，可检测胸腺生成素浓度大于 5 ng/ml。放射免疫分析发展的一个关键点是通过 Bolton-Hunter 方法制备 125I 标记的胸腺生成素，因为酪氨酰残基的直接碘化会损害胸腺生成素的免疫反应性。
A radioimmunoassay for thymopoietin was developed that detects thymopoietin concentrations greater than 5 ng/ml. A critical point in development of the radioimmunossay was preparation of 125I-labeled thymopoietin by the Bolton-Hunter method, since direct iodination of tyrosyl residues impaired the immunoreactivity of thymopoietin.