Spectral optical coherence tomography findings in adult-onset foveomacular vitelliform dystrophy
Spectral optical coherence tomography findings in adult-onset foveomacular vitelliform dystrophy
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DOI：
10.1055/s-2008-1027309
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发表时间：
2008-05-01
影响因子：
0.8
通讯作者：
Matter, M. A.
中科院分区：
文献类型：
--
作者：
Petropoulos, I. K.;Desmangles, P. M.;Matter, M. A.
背景：成人型黄斑凹卵黄样营养不良（AOFVD）是典型的双侧对称性疾病。我们目前的光谱光学相干断层扫描（OCT）的结果在两个病人与单侧AOFVD.Patients和方法：病例1代表一个76岁的男子在过去6年的血管造影在他的右眼黄斑病变。右眼的视力从1.0下降到0.6。病例2，69岁男性，右眼视力模糊。右眼视力为0.7，左眼视力为1.0。结果：例1荧光血管造影显示中心凹旁有一个约2/3大小的高荧光病变，无迟发性渗漏。OCT显示位于视网膜色素上皮（RPE）和感光细胞层之间的厚壁椭圆形囊性病变。在第2例中，OCT显示一个高反射性圆形病变也位于RPE和感光层之间，提升覆盖的内层retina.Conclusions：光谱OCT能够增强视网膜层的可视化，并提供有用的信息，关于AOFVD的诊断和确切位置。
Background: Adult-onset foveomacular vitelliform dystrophy (AOFVD) is typically bilateral and symmetrical. We present the spectral optical coherence tomography (OCT) findings in two patients with unilateral AOFVD.Patients and Methods: Case 1 represents a 76-year-old man followed angiographically over the last 6 years for a macular lesion in his right eye. Visual acuity in the right eye has decreased from 1.0 to 0.6. In case 2, a 69-year-old man presented with blurred vision in his right eye. Visual acuity was 0.7 in the right eye and 1.0 in the left eye. In both patients, spectral OCT (Copernicus SOCT System) was performed.Results: In case 1, fluorescein angiography showed a juxtafoveal hyperfluorescent lesion 2/3 of disc area in size, without late leakage. OCT showed a cystic oval lesion with thick walls, located between the retinal pigment epithelium (RPE) and photoreceptor layers. In case 2, OCT showed a hyperreflective round lesion also located between the RPE and photoreceptor layers, elevating the overlying inner retina.Conclusions: Spectral OCT enables enhanced visualization of the retinal layers and provides useful information regarding the diagnosis and the exact location of AOFVD.