Natural functions of bacterial multidrug transporters

Natural functions of bacterial multidrug transporters
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DOI:
10.1016/s0966-842x(97)01064-0
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发表时间:
1997-08-01
影响因子:
15.9
通讯作者:
Neyfakh, AA
Neyfakh, AA
中科院分区:
生物学1区
文献类型:
--
作者:
Neyfakh, AA

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细菌表达几种多药物转运蛋白,这些转运蛋白可以识别结构不同的有毒分子并将其从细胞中排出。这些转运蛋白可能已经进化来保护细菌免受多种环境毒素的侵害,或者转运特定的生理化合物,并具有排出药物的能力,这只是偶然的副作用。
Bacteria express several multidrug transporters that recognize structurally dissimilar toxic molecules and expel them from cells. These transporters may have evolved to protect bacteria from diverse environmental toxins or to transport specific physiological compounds with the ability to expel drugs being only a fortuitous side effect.