Eosinophil overview: structure, biological properties, and key functions.

Eosinophil overview: structure, biological properties, and key functions.
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嗜酸性粒细胞概述:结构、生物学特性和关键功能。

DOI:
10.1007/978-1-4939-1016-8_1
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发表时间:
2014
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
通讯作者:
Walsh,GarryM
Walsh,GarryM
中科院分区:
--
文献类型:
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作者:
Lacy,Paige;Rosenberg,HeleneF;Walsh,GarryM

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嗜酸性粒细胞是一种神秘的细胞,具有持续迷人的能力。嗜酸性粒细胞生物学的研究历程可以追溯到19世纪。也许嗜酸性粒细胞最令人着迷的方面之一是,积累的知识如何改变了对其功能的认识,从被动的旁观者,炎症调节剂,到装载组织毒性物质的强大效应细胞,再到最近认识到它可以在先天和适应性免疫中作为复杂事件的积极和消极调节因子。这本书由26章写的专家在嗜酸性粒细胞生物学领域,提供全面的和明确的书面协议的技术,旨在巩固研究到嗜酸性细胞的功能在健康和疾病。
The eosinophil is an enigmatic cell with a continuing ability to fascinate. A considerable history of research endeavor on eosinophil biology stretches from the present time back to the nineteenth century. Perhaps one of the most fascinating aspects of the eosinophil is how accumulating knowledge has changed the perception of its function from passive bystander, modulator of inflammation, to potent effector cell loaded with histotoxic substances through to more recent recognition that it can act as both a positive and negative regulator of complex events in both innate and adaptive immunity. This book consists of 26 chapters written by experts in the field of eosinophil biology that provide comprehensive and clearly written protocols for techniques designed to underpin research into the function of the eosinophil in health and disease.