Cardiac atrioventricular junctional tissues in hearts from infants who died suddenly.
Cardiac atrioventricular junctional tissues in hearts from infants who died suddenly.
复制标题
猝死婴儿心脏中的房室交界组织。
DOI：
10.1016/s0735-1097(85)80022-x
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发表时间：
1985
影响因子：
24
通讯作者：
Kane,BM
中科院分区：
文献类型：
--
作者：
Marino,TA;Kane,BM
婴儿猝死综合征的原因目前尚不清楚。大多数人同意，在大多数情况下，它涉及到原发性呼吸暂停。然而，心脏异常可能是这些死亡的一部分。对心脏房室交界处组织结构的研究将有助于深入了解可能由心脏形态异常引起的婴儿猝死的频率。对7例确诊为婴儿猝死综合征的婴儿心脏进行连续切片和研究，根据心脏的形态特征将其分为3组。在第一组中，以两例为代表，与正常相比有明显的差异，最显著的特征是存在旁路。第二组4例，房室交界组织未完全成熟，AY结节细胞和束状细胞散在分布于纤维环内。第三组结合部组织结构正常。仍然有一组明显的婴儿可能突然和意外地死于心脏异常，这需要更完整的定义。
The cause of sudden infant death syndrome is not known at present. Most agree that in the majority of cases it involves primary apnea. However, cardiac abnormalities probably account for a subset of these deaths. An investigation into the structure of the atrioventricular (A V) junctional tissues of the heart would provide insight into the frequency of sudden death in infants that might result from abnormal cardiac morphology. The hearts of seven infants who died from diagnosed sudden infant death syndrome were examined by serially sectioning and studying this critical region of the heart.The hearts of these infants could be divided into three groups on the basis of their morphologic features. In the first group, represented by two cases, there were marked variations from normal, the most striking feature being the presence of accessory pathways. In the second group, represented by four cases, the A V junctional tissues were not fully mature and clusters of AY nodal and bundle cells were dispersed throughout the anulus fibrosus. In the third group, the structure of the junctional tissues was normal. There remains a distinct subset of infants who might have died suddenly and unexpectedly from cardiac abnormalities that needs to be more completely defined.