What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
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DOI：
10.1177/1179069519859371
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发表时间：
2019-06-23
影响因子：
--
通讯作者：
Cline, Hollis T.
中科院分区：
文献类型：
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作者：
He, Hai-yan;Cline, Hollis T.
近年来，神经回路中兴奋与抑制之间的平衡越来越受到人们的关注，因为它在正常神经回路中具有多方面的功能，并且在许多神经系统疾病的病因学中具有潜在的作用。在这里，我们讨论了通过实验测量明确定义兴奋/抑制的重要性，以及最近一些研究对我们理解神经元水平上的兴奋/抑制调节的意义。
The balance between excitation and inhibition in neuronal circuits has drawn more and more attention in recent years, due to its proposed multifaceted functions in the normal neural circuit as well as its potential roles in the etiology of many neurological disorders. Here, we discuss the importance of clearly defining excitation/inhibition by experimental measurements and the implications of some recent studies to our understanding of the regulation of excitation/inhibition at the neuronal level.