MESENCHYMAL CHONDROSARCOMA - A CYTOGENETIC, IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL-STUDY

MESENCHYMAL CHONDROSARCOMA - A CYTOGENETIC, IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL-STUDY
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DOI:
10.1016/0165-4608(95)00031-3
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发表时间:
1995-08-01
影响因子:
--
通讯作者:
SPEIGHTS, VO
SPEIGHTS, VO
中科院分区:
其他
文献类型:
--
作者:
DOBIN, SM;DONNER, LR;SPEIGHTS, VO

文献摘要

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研究了一例间叶性软骨肉瘤。肿瘤接近四倍体,克隆结构染色体异常包括add(7)(p13)、add(22)(q13)、标记物和双分钟。超微结构和免疫组化结果与诊断一致。结蛋白的强免疫反应性是肿瘤的一个不寻常的、以前未报道过的特征。
A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.