An Efficient Iron(III)-Catalyzed Aerobic Oxidation of Aldehydes in Water for the Green Preparation of Carboxylic Acids.
An Efficient Iron(III)-Catalyzed Aerobic Oxidation of Aldehydes in Water for the Green Preparation of Carboxylic Acids.
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DOI：
10.1002/anie.201612225
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发表时间：
2017-03
影响因子：
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通讯作者：
Han Yu;Shi Ru;Guo-Fa Dai;Yongyan Zhai;Hua-lin Lin;Sheng Han;Yongge Wei
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文献类型：
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作者：
Han Yu;Shi Ru;Guo-Fa Dai;Yongyan Zhai;Hua-lin Lin;Sheng Han;Yongge Wei
开发了非均相铁（III）催化的水中醛的有氧氧化的第一个实例。该方法利用1个大气压的氧气作为唯一的氧化剂，在极其温和的水性条件下进行，并且涵盖了广泛的各种官能化醛。色谱法通常不是产品纯化所必需的。其操作简单，克级氧化，并能够连续重复使用的催化剂，使这种新的方法环境友好和成本效益。这种方法的通用性使其具有在工业规模上使用的潜力。
The first example of a heterogeneous iron(III)-catalyzed aerobic oxidation of aldehydes in water was developed. This method utilizes 1 atmosphere of oxygen as the sole oxidant, proceeds under extremely mild aqueous conditions, and covers a wide range of various functionalized aldehydes. Chromatography is generally not necessary for product purification. Its operational simplicity, gram-scale oxidation, and the ability to successively reuse the catalyst, make this new methodology environmentally benign and cost effective. The generality of this methodology gives it the potential to be used on an industrial scale.