International trends in the incidence of testicular cancer, 1973-2002.
International trends in the incidence of testicular cancer, 1973-2002.
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DOI：
10.1158/1055-9965.epi-10-0031
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发表时间：
2010-05
期刊：
影响因子：
--
通讯作者：
McGlynn KA
中科院分区：
文献类型：
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作者：
Chia VM;Quraishi SM;Devesa SS;Purdue MP;Cook MB;McGlynn KA
虽然在北方欧洲血统人群中广泛报告了睾丸癌发病率，但对其他人群的发病率检查较少。在先前的报告中，总结了1973-1997年全球睾丸癌发病率和趋势。目前的报告扩展了这些分析，增加了五大洲癌症发病率的5年数据。获得了美洲、亚洲、欧洲和大洋洲人群连续5年的标准化发病率。总的来说，睾丸癌发病率在北方欧洲人群中仍然最高（每10万人中8.0-9.0人），在亚洲和非洲人群中最低（每10万人中<1人）。然而，这一模式的一个显著例外是智利瓦尔迪维亚登记处报告的发生率非常高（每100，000人中有8.8人）。在许多人群中，发病率在1973年至2002年期间上升，尽管欧洲血统人群中的增长最强劲，最一致。在一些欧洲人群中，如丹麦和瑞士日内瓦的人群，近年来的发病率明显趋于平稳。几乎没有证据表明东亚人群的发病率增加，可能有证据表明东亚人群的发病率略有下降。一般而言，组织学（腺瘤，非腺瘤）的趋势彼此相似。睾丸癌的风险在北方欧洲人群中仍然很高，在亚洲和非洲人群中很低。北方欧洲人发病率上升和东亚人发病率稳定或下降的原因尚不清楚，支持未来病因学研究的必要性。
While testicular cancer incidence rates have been widely reported in populations of Northern European ancestry, rates in other population have been less frequently examined. In a prior report, global testicular cancer incidence rates and trends for the years 1973–1997 were summarized. The current report extends these analyses with an additional 5 years of data from Cancer Incidence in Five Continents. Age-standardized incidence rates over successive 5-year time periods were obtained for populations in the Americas, Asia, Europe, and Oceania. In general, testicular cancer incidence remained highest in Northern European populations (8.0–9.0 per 100,000) and lowest in Asian and African populations (<1 per 100,000). One notable exception to this pattern, however, was the very high rate reported by the Valdivia, Chile registry (8.8 per 100,000). In many populations, incidence rates rose between 1973 and 2002, although the increases were strongest and most consistent among populations of European ancestry. In some European populations, such as those of Denmark and of Geneva, Switzerland, some plateauing of rates was evident in recent years. There was little evidence of increase and possible evidence of modest decline in rates in east Asian populations. In general, the trends by histology (seminoma, nonseminoma) were similar to one another. Risk of testicular cancer remains high in Northern European populations and low in Asian and African populations. Reasons for increasing rates among Northern Europeans and more stable or declining rates among East Asians are unexplained, supporting the need for future etiologic studies.