Associations between diabetes, major depressive disorder and generalized anxiety disorder comorbidity, and disability: Findings from the 2012 Canadian Community Health Survey - Mental Health (CCHS-MH)
Associations between diabetes, major depressive disorder and generalized anxiety disorder comorbidity, and disability: Findings from the 2012 Canadian Community Health Survey - Mental Health (CCHS-MH)
复制标题
DOI：
10.1016/j.jpsychores.2014.11.023
复制
发表时间：
2015-02-01
影响因子：
4.7
通讯作者：
Schmitz, Norbert
中科院分区：
文献类型：
--
作者：
Deschenes, Sonya S.;Burns, Rachel J.;Schmitz, Norbert
目的：检查糖尿病、残疾与共病重度抑郁症（MDD）和广泛性焦虑症（GAD）的可能性之间的关系。方法：数据来自2012年加拿大社区健康调查心理健康（N = 17623）。糖尿病评估包括由医疗保健专业人员进行的自我报告的糖尿病诊断。残疾通过自我报告进行评估。12-采用复合国际诊断访谈3.0评估月和终生MDD和GAD。在调整了社会人口统计学和健康相关因素的多项逻辑回归模型中，糖尿病与12个月MDD和GAD共病的可能性更大相关。（OR = 1.99，95% CI [1.22，3.25]，p = 0.006）。没有发现MDD与GAD或GAD与MDD的显著相关性。当考虑MDD和GAD的终身诊断时，这种效应模式仍然存在。对于糖尿病患者（n = 1730），调整的二元logistic回归模型显示，在12个月的诊断中，（OR = 2.79，95% CI [139-5.621，p = .004），GAD不伴MDD（OR = 3.69，95%CI [1.34-10.11]，p = 0.01）和MDD和GAD共病（OR = 4.17，95%CI [1.66-10.51]，p = 0.002）与比对照组更大的残疾相关。只有共病MDD和GAD与残疾时，MDD和GAD的终身诊断被认为considered.Conclusions：糖尿病患者可能特别容易共病MDD和GAD，MDD-GAD共病可能会加剧残疾的糖尿病患者。(C)2014爱思唯尔公司All rights reserved.
Objective: To examine the associations between diabetes, disability, and the likelihood of comorbid major depressive disorder (MDD) and generalized anxiety disorder (GAD).Methods: Data were obtained from the 2012 Canadian Community Health Survey Mental Health (N = 17623). Diabetes assessment consisted of a self-reported diagnosis of diabetes made by a health care professional. Disability was assessed via self-report. 12-Month and lifetime MDD and GAD were assessed with the Composite International Diagnostic Interview 3.0.Results: In multinomial logistic regression models adjusted for sociodemographic and health-related factors, having diabetes was associated with a greater likelihood of 12-month comorbid MDD and GAD (OR = 1.99, 95% CI [1.22, 3.25], p = .006), compared with those with neither MDD nor GAD. No significant associations were found for MDD without GAD or GAD without MDD. This pattern of effects held when lifetime diagnoses of MDD and GAD were considered. For individuals with diabetes (n = 1730), adjusted binary logistic regression models demonstrated that with 12-month diagnoses, MDD without GAD (OR = 2.79,95% CI [139-5.621, p = .004), GAD without MDD (OR = 3.69,95% CI [1.34-10.11], p =.01), and comorbid MDD and GAD (OR = 4.17, 95% CI [1.66-10.51], p = .002) were associated with greater disability than the control group. Only comorbid MDD and GAD were associated with disability when lifetime diagnoses of MDD and GAD were considered.Conclusions: Individuals with diabetes may be particularly vulnerable to comorbid MDD and GAD, and MDD-GAD comorbidity may exacerbate disability in persons with diabetes. (C) 2014 Elsevier Inc. All rights reserved.