NOMENCLATURE FOR CENTROMERIC POSITION ON CHROMOSOMES
NOMENCLATURE FOR CENTROMERIC POSITION ON CHROMOSOMES
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DOI：
10.1111/j.1601-5223.1964.tb01953.x
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发表时间：
1964-01-01
期刊：
影响因子：
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通讯作者：
SANDBERG, AA
中科院分区：
文献类型：
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作者：
LEVAN, A;FREDGA, K;SANDBERG, AA
对着丝粒在染色体上的位置提出了一个标准化的命名方法。染色体长度的一半被分成4个大小相等的区域，从中间开始，称为m(中位区)、sm(亚中位区)、st(亚端区)和t(终端区)。此外，确切的染色体中间称为[图像]，最末端T。这些术语主要是指着丝粒的位置，但也可以用来表示染色体上的所有其他形态位置。讨论了着丝粒位置的其他术语的历史上的一些特征。可以使用术语中部着丝粒、亚中部着丝粒、亚端着丝粒和顶端着丝粒作为m、sm、as和t的同系体，但后一种术语更可取。在我们的系统中，末端着丝点用T表示，指的是染色体的终点。无着丝粒是末端着丝点的反义词，指的是染色体上的所有其他位置。
A standardized nomenclature is suggested for centromeric position on chromosomes. Half the length of the chromosme is divided into 4 equally-sized regions which, starting from the middle, are called m (median region), sm (submedian), st (subterminal) and t (terminal region). In addition, the exact chromosome middle is called [image], the very end T. The terms primarily refer to the location of the centromere, but may well be used to indicate all other morphologic locations on chromosomes. Some features of the history of other terminologies for centromeric locations are discussed. It is possible to use the terms metacentric, submetacentric, subtelocentric and acrocentric as synomyms to m, sm, as and t, but the latter terms are preferable. Telocentric is symbolized with T in our system and refers to the end point of the chromosome. Atelocentric is the opposite of telocentric and means all other positions on the chromosome.