Survival, strobilation and sexual maturation of Echinococcus multilocularis in the small intestine of golden hamsters
Survival, strobilation and sexual maturation of Echinococcus multilocularis in the small intestine of golden hamsters
复制标题
多房棘球绦虫在金黄地鼠小肠中的存活、颤动和性成熟
DOI：
10.1017/s0031182000060194
复制
发表时间：
1990
期刊：
影响因子：
2.4
通讯作者：
H. Sato
中科院分区：
文献类型：
--
作者：
M. Kamiya;H. Sato
多房棘球蚴在6周龄雄性金仓鼠的小肠中存活、交配和性成熟，这些雄性金仓鼠要么没有接受治疗，要么接受强的松龙叔丁乙酸酯（PTBA）治疗，口服20000个原头节。未接受治疗的仓鼠在感染后携带成虫长达25天（p.i.）。从感染之日起（第0天）接受PTBA治疗的仓鼠比未接受PTBA治疗的仓鼠拥有更多的成虫，并且它们的生存期延长。此外，在第- 14天和- 12天额外使用PTBA的仓鼠中，观察到蠕虫的恢复，发育和存活时间显著改善，蠕虫的发育包括proglottisation，性成熟和卵子形成与狗相当。以多房棘球绦虫/金仓鼠为代表的棘球绦虫/啮齿动物系统可能会使目前停滞不前的棘球绦虫终宿主期和卵期宿主-寄生虫相互作用的研究重新活跃起来。
Summary Echinococcus multilocularis survived, strobilated and matured sexually in the small intestine of 6-week-old male golden hamsters that were either non-treated or treated with prednisolone tertiary-butylacetate (PTBA), following oral administration of 20000 protoscoleces. Non-treated hamsters harboured the adult worms for up to 25 days post-infection (p.i.). Hamsters treated with PTBA from the day of infection (day 0 p.i.) harboured more adults than the non-treated, and their survival periods were extended. Moreover, a remarkable improvement in worm recovery, development and survival periods was observed in hamsters additionally treated with PTBA on days — 14 and — 12 p.i., and the worm development including proglottisation, sexual maturation and egg formation was comparable with that in dogs. With the present results it is suggested that Echinococcus/rodent systems represented by the E. multilocularis/golden hamsters may rejuvenate the current stagnant research on host-parasite interactions of the definitive host-stage and egg-stage of Echinococcus.