Chemical Studies on Light Chains from Cardiac and Skeletal Muscle Myosins

Chemical Studies on Light Chains from Cardiac and Skeletal Muscle Myosins
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心脏和骨骼肌肌球蛋白轻链的化学研究

DOI:
10.1038/234085a0
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发表时间:
1971
期刊:
影响因子:
64.8
通讯作者:
B. Pope
B. Pope
中科院分区:
综合性期刊1区
文献类型:
--
作者:
A. Weeds;B. Pope

文献摘要

被引文献

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在心肌肌球蛋白和骨骼肌肌球蛋白的轻链硫醇序列中观察到差异。来自牛和羊心脏的心脏轻链含有相同的硫醇序列(肽 A),该序列存在于兔和羊骨骼肌球蛋白的“碱”轻链中,但具有两个额外的硫醇序列(肽 B 和 C)。心肌肌球蛋白轻链和慢骨骼肌肌球蛋白轻链之间的化学相似性已被证明。
Differences have been observed in the thiol sequences of light chains from cardiac and skeletal muscle myosins. Cardiac light chains from both bovine and sheep hearts contain the same thiol sequence (peptide A) which is present in the “alkali” light chains of rabbit and sheep skeletal myosin, but have two extra thiol sequences (peptides B and C). Chemical similarities have been demonstrated between myosin light chains from cardiac and slow skeletal muscle.