An intervention to decrease catheter-related bloodstream infections in the ICU
An intervention to decrease catheter-related bloodstream infections in the ICU
复制标题
DOI：
10.1056/nejmoa061115
复制
发表时间：
2006-12-28
影响因子：
158.5
通讯作者：
Goeschel, Christine
中科院分区：
文献类型：
--
作者：
Pronovost, Peter;Needham, Dale;Goeschel, Christine
背景：导管相关的血流感染发生在重症监护病房（ICU）是常见的，昂贵的，并可能lethal.METHODS：我们进行了一项合作的队列研究，主要是在密歇根州的ICU。采用循证干预措施降低导管相关血流感染的发生率。使用多水平泊松回归模型比较研究干预实施前、期间和实施后18个月内的感染率。感染率每1000导管天，测量在3个月的时间间隔，根据国家医院感染监测系统的指南。结果：共有108个ICU同意参加这项研究，103个报告的数据。该分析包括1981个ICU月的数据和375，757个导管日。每1000导管日导管相关血流感染的中位发生率从基线时的2.7例感染降至实施研究干预后3个月的0例（P
BACKGROUND:Catheter-related bloodstream infections occurring in the intensive care unit (ICU) are common, costly, and potentially lethal.METHODS:We conducted a collaborative cohort study predominantly in ICUs in Michigan. An evidence-based intervention was used to reduce the incidence of catheter-related bloodstream infections. Multilevel Poisson regression modeling was used to compare infection rates before, during, and up to 18 months after implementation of the study intervention. Rates of infection per 1000 catheter-days were measured at 3-month intervals, according to the guidelines of the National Nosocomial Infections Surveillance System.RESULTS:A total of 108 ICUs agreed to participate in the study, and 103 reported data. The analysis included 1981 ICU-months of data and 375,757 catheter-days. The median rate of catheter-related bloodstream infection per 1000 catheter-days decreased from 2.7 infections at baseline to 0 at 3 months after implementation of the study intervention (P