Immunohistochemical characteristics of polymyositis in patients with HTLV‐1–associated myelopathy and HTLV‐I carriers
Immunohistochemical characteristics of polymyositis in patients with HTLV‐1–associated myelopathy and HTLV‐I carriers
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HTLV-1-相关性脊髓病和HTLV-I携带者多发性肌炎的免疫组织化学特征
DOI：
10.1002/mus.880160507
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发表时间：
1993
期刊：
影响因子：
3.4
通讯作者：
M. Osame
中科院分区：
文献类型：
--
作者：
I. Higuchi;E. Montemayor;Syuji Izumo;M. Inose;M. Osame
研究了HTLV‐I相关性脊髓病（HAM）患者和HTLV‐I携带者中多发性肌炎的免疫组织化学特征。浸润细胞主要是T细胞，与对照组无差异。所有标本均含有MHC I类抗原阳性染色的肌纤维，但在1例HTLV-I阴性多发性肌炎患者、3例HTLV-I阳性多发性肌炎患者和所有5例HAM多发性肌炎患者的一些肌纤维中也表达II类抗原。HAM患者神经细胞粘附分子表达最低。这些发现可能提示多发性肌炎伴HAM患者存在不同的免疫环境。© 1993 John Wiley & Soncs，Inc.
The immunohistochemical characteristics of polymyositis in patients with HTLV‐I‐associated myelopathy (HAM) and HTLV‐I carriers were studied. Infiltrating cells were predominantly T cells and were not different from in the control group. All specimens contained positively staining muscle fibers for MHC class I antigens, but class II antigens were also expressed in some muscle fibers in 1 patient with HTLV‐I‐negative polymyositis, 3 patients with HTLV‐I‐positive polymyositis, and all 5 HAM patients with polymyositis. Expression of the neural cell adhesion molecule was lowest in the HAM patients. These findings may suggest a different immune environment in polymyositis with HAM. © 1993 John Wiley & Soncs, Inc.
逆转录病毒诱导的主要组织相容性复合物抗原表达的变化影响细胞毒性 T 淋巴细胞裂解的易感性。
DOI：
--
发表时间：
1985
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Flyer,DC;Burakoff,SJ;Faller,DV
通讯作者：
Faller,DV
影响因子：
3.3
作者：
EMSLIESMITH, AM;ARAHATA, K;ENGEL, AG
通讯作者：
ENGEL, AG