Developing Researchers with Expertise in Sex as a Biological Variable through SCORE Career Enhancement Core Center Programs.
Developing Researchers with Expertise in Sex as a Biological Variable through SCORE Career Enhancement Core Center Programs.
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通过 SCORE 职业提升核心中心项目培养具有性别作为生物变量专业知识的研究人员。
DOI：
10.1089/jwh.2023.0015
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
McKee,SherryA
中科院分区：
文献类型：
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作者：
Zakiniaeiz,Yasmin;Peltier,MacKenzieR;Mineur,YannS;Gueorguieva,Ralitza;Picciotto,MarinaR;Petrakis,Ismene;Cosgrove,KellyP;McKee,SherryA
迫切需要跨学科和转化科学家将性别作为生物变量（SABV）研究应用于解决妇女健康方面的知识差距。2018年，妇女健康研究办公室（ORWH）与美国国立卫生研究院（NIH）的几个研究所和中心合作，扩大了具有重要特征的专业研究中心（SCOR）卓越（SCORE）计划（统称为SCOR/E） -职业提升核心（CEC）。SCORE CEC指导早期职业研究人员成为关注SABV和妇女健康的下一代生物医学和行为研究人员。在这篇文章中，我们概述了耶鲁大学SCORE通过提供工资支持、教育课程、翻译指导、试点项目资金和专业发展来支持早期职业轨迹的方法。使用耶鲁- scor /E CEC项目作为教学模式，我们强调了早期职业研究者学术成功的关键指标，即资助资金和出版物。在耶鲁大学，由SCOR/E项目资助的12个试点项目产生了14笔校外赠款，相当于每1美元的“种子”资金投资可获得80美元的回报。到目前为止，我们的SCOR/E项目已经产生了129篇出版物，其中83%是学员的第一作者，并且100%的学员继续以SABV为重点进行研究。最后，我们就生物医学科学家如何以跨学科和综合的方式将SABV应用于主要医学条件的研究提出了建议。
There is a critical need for interdisciplinary and translational scientists to apply sex as a biological variable (SABV) research to address knowledge gaps in the health of women. In 2018, the Office of Research on Women's Health (ORWH) partnered with several National Institute of Health (NIH) Institutes and Centers to expand the Specialized Centers of Research (SCOR) Excellence (SCORE) Programs (together referred to as SCOR/E) with an important feature—the Career Enhancement Core (CEC). The SCORE CEC mentors early career investigators to become the next generation of biomedical and behavioral researchers focused on SABV and women's health. In this article, we outline our approach at the Yale University SCORE to support early career trajectories through the provision of salary support, educational curricula, translational mentorship, pilot project funding, and professional development. Using the Yale-SCOR/E CEC Programs as instructional models, we highlight critical measures of academic success, namely grant funding and publications, among early career investigators. At Yale University, 12 pilot projects funded by the SCOR/E Programs resulted in 14 extramural grants, amounting to an $80 return on every $1 invested in “seed” funding. So far, our SCOR/E Programs have resulted in 129 publications, 83% of which were first-authored by trainees, and 100% of trainees continued research careers with an emphasis on SABV. Finally, we provide recommendations on how biomedical scientists can apply SABV in their studies of major medical conditions in an interdisciplinary and integrative way.