Anion binding properties for pyrophosphate derived from a 2,6-diamidopyridinedipyrromethane macrocycle
Anion binding properties for pyrophosphate derived from a 2,6-diamidopyridinedipyrromethane macrocycle
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DOI：
10.1007/s11696-021-01554-6
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发表时间：
2021-04
期刊：
影响因子：
2.2
通讯作者：
Rui Yi;Xingli Liu;Zhenglin Tang;Chao Huang;B. Zhu;Chun Zhu
中科院分区：
文献类型：
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作者：
Rui Yi;Xingli Liu;Zhenglin Tang;Chao Huang;B. Zhu;Chun Zhu
通过Schiff碱缩合反应合成了2，6-二氨基吡啶二吡咯甲烷大环受体。通过单晶X射线衍射（SC-XRD）分析了游离大环及其与H2 P2 O 72 −的配合物的结构。受体与HP 2 O 73-的四丁基铵盐结合的稳定常数通过使用乙腈溶液的等温滴定量热法测定。根据滴定数据，该受体与HP 2 O 73 −表现出高亲和力。晶体结构分析表明，该大环受体通过质子化反应生成中性的焦磷酸盐配合物。
A 2,6-diamidopyridinedipyrromethane macrocyclic receptor was prepared by a Schiff base condensation reaction. The structures of the free macrocycle and its complex with H2P2O72−were analyzed by single crystal X-ray diffraction (SC-XRD). The stability constants for the binding of the receptor with tetrabutylammonium salts of HP2O73−were determined by isothermal titration calorimetry using acetonitrile solutions. According to the titration data, the receptor exhibited high affinity with HP2O73−. The crystal structure analysis demonstrated that the neutral sandwich-type pyrophosphate complex was formed via the protonation of the macrocyclic receptor.