BoS: A Large and Diverse Family of Short Interspersed Elements (SINEs) in Brassica oleracea
BoS: A Large and Diverse Family of Short Interspersed Elements (SINEs) in Brassica oleracea
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BoS：甘蓝中大量且多样化的短散布元素 (SINE) 家族
DOI：
10.1007/s00239-004-0259-5
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发表时间：
2005
影响因子：
3.9
通讯作者：
S. Wessler
中科院分区：
文献类型：
--
作者：
Xiaoyu Zhang;S. Wessler
短散布元件（西内斯）是分布在真核生物基因组中的非自主的非LTR反转录转座子。许多SINE家族已在动物中被确定，而在植物中只有少数被描述。在这里，我们描述了一个新的家庭的西内斯，命名为BoS，这是广泛的油菜科和目前在102000个拷贝的甘蓝。除了与先前描述的西内斯共享模块化结构和靶位点偏好之外，BoS元件还具有几个不寻常的特征。首先，BoS RNA的头部区域可以采用独特的发夹样二级结构。其次，BoS有15个不同的亚家族，是迄今为止描述的最多样化的SINE家族之一。第三，几个亚家族具有镶嵌结构，这是通过现有亚家族之间的序列交换而产生的，可能是在反转录转座过程中。对BoS亚科的分析表明，它们在十字花科进化的不同时期都很活跃，并且活性成分可能仍然存在于一些芸苔属物种中。因此，BoS元件可能是一个有价值的工具，作为系统发育标记，解决悬而未决的问题，在植物科的物种进化。
Short interspersed elements (SINEs) are nonautonomous non-LTR retrotransposons that populate eukaryotic genomes. Numerous SINE families have been identified in animals, whereas only a few have been described in plants. Here we describe a new family of SINEs, named BoS, that is widespread in Brassicaceae and present at ∼2000 copies in Brassica oleracea. In addition to sharing a modular structure and target site preference with previously described SINEs, BoS elements have several unusual features. First, the head regions of BoS RNAs can adopt a distinct hairpin-like secondary structure. Second, with 15 distinct subfamilies, BoS represents one of the most diverse SINE families described to date. Third, several of the subfamilies have a mosaic structure that has arisen through the exchange of sequences between existing subfamilies, possibly during retrotransposition. Analysis of BoS subfamilies indicate that they were active during various time periods through the evolution of Brassicaceae and that active elements may still reside in some Brassica species. As such, BoS elements may be a valuable tool as phylogenetic makers for resolving outstanding issues in the evolution of species in the Brassicaceae family.
影响因子：
5.6
作者：
Muddashetty, RS;Khanam, T;Brosius, J
通讯作者：
Brosius, J
SINE RNP 的共享蛋白质成分。
影响因子：
5.6
作者：
West,Neva;Roy-Engel,AstridM;Imataka,Hiroaki;Sonenberg,Nahum;Deininger,Prescott
通讯作者：
Deininger,Prescott