Clinico-statistical investigation of wound healing in oral surgery cases using the technique of covering the wound with fibrin glue spray and polyglycolic acid sheet
Clinico-statistical investigation of wound healing in oral surgery cases using the technique of covering the wound with fibrin glue spray and polyglycolic acid sheet
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纤维蛋白胶喷雾和聚乙醇酸片覆盖伤口技术对口腔手术病例伤口愈合的临床统计研究
DOI：
10.11277/stomatology.62.5
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
A. Kaetsu
中科院分区：
文献类型：
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作者：
Fumitaka Terasawa;T. Shirozu;Mawoomi Moon;T. Tatematsu;A. Kouketsu;A. Kaetsu
聚乙醇酸（PGA）片材是由聚乙醇酸组成的具有一定弹性的无纺布制成的生物可吸收缝线增强材料。在胸外科、胃肠外科中，与纤维蛋白胶一起用于组织缺损的加固或缝合。近年来，其在口腔颌面外科中的应用已有所报道。我们于2010年9月至2011年9月对我科20例口腔手术患者（20个部位）应用PGA片及纤维蛋白胶喷雾覆盖创面的预后因素（手术部位、切除面积、禁食期、PGA片附着天数）进行临床统计学评价。禁食时间与PGA片附着天数、切除面积与PGA片附着天数无显著相关性。PGA片的手术部位和附着时间差异有统计学意义（p< 0.01）。因此，术后禁食期不影响PGA片的早期剥离。为了防止PGA片的早期脱离，我们考虑了附着位置，并设计了一种将PGA片附着在无骨支撑区域后进行边缘缝合的方法。在这类患者的口腔手术中，建议采取适当的步骤，并根据手术情况适当考虑组织损失的数量。
Polyglycolic acid (PGA) sheet is a bioabsorbable suture reinforcement consisting of polyglycolide, made of nonwoven fabric with some elasticity. It has been used for strengthening tissue defects or suturing together with fibrin glue in thoracic surgery and gastroenterological surgery. Recently, its application to oral and maxillofacial surgery has been reported. We clinico-statistically evaluated prognostic factors (operation site, excised area, fasting period, attachment days of PGA sheet) in 20 oral surgery patients (20 sites) followed by a technique of covering the wound with a PGA sheet and fibrin glue spray, between September 2010 and September 2011 in our department. There were no significant correlations between fasting period and attachment days of the PGA sheet, or between the excised area and attachment days of the PGA sheet. There were significant differences (p< 0.01) between the operation site and attachment days of the PGA sheet. As a result, the fasting period after the operation was not involved in early detachment of the PGA sheet. To prevent early detachment of the PGA sheet, we considered the attachment position and devised a way of suturing the PGA sheet margin after the sheet was attached to the region not supported by bone. In oral surgery for such patients, appropriate steps are suggested with due consideration for the amount of tissue loss depending on the operation.