A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children
A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children
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DOI：
10.1016/j.jcv.2007.07.001
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发表时间：
2007-09-01
影响因子：
8.8
通讯作者：
Sloot, Theo P.
中科院分区：
文献类型：
--
作者：
Bialasiewicza, Seweryn;Whiley, David M.;Sloot, Theo P.
背景资料：最近，Allander等报道了在急性呼吸道感染（阿尔蒂）患者的呼吸道分泌物中发现了一种新的人类多瘤病毒KI病毒。目的：我们检测了2002年11月至2003年8月在澳大利亚昆士兰州收集的951份呼吸道感染患者的呼吸道样本中是否存在KI病毒。24份（2.5%）样本为KI病毒阳性，其中20份（83%）来自5岁以下儿童。在6名（25%）患者中，同时检测到KI与另一种病毒。三个分离株的全基因组测序显示高度的保守性之间的昆士兰州的分离株和原始分离株报道从瑞典patient.Conclusions：新描述的KI多瘤病毒可能是常见的呼吸道患者与阿尔蒂，特别是儿童，结果表明，该病毒具有全球性的存在。皇冠版权所有（C）2007年出版的爱思唯尔B.V.保留所有权利。
Background: Recently, Allander and co-workers reported the discovery of a new human polyomavirus, KI virus, in respiratory secretions from patients with acute respiratory tract infection (ARTI).Objective: We examined 951 respiratory samples collected in Queensland, Australia, between November 2002 and August 2003 from patients with respiratory infection, for the presence of the KI virus.Results: Twenty-four (2.5%) samples were positive for KI virus with 20 (83%) of these from children younger than 5 years. In six (25%) patients KI was co-detected with another virus. Full genome sequencing of three isolates shows a high degree of conservation between the Queensland isolates and the original isolates reported from Swedish patients.Conclusions: The newly described KI polyomavirus may commonly be found in the respiratory tract of patients with ARTI, particularly children, and results indicate that the virus has global presence. Crown Copyright (C) 2007 Published by Elsevier B.V. All rights reserved.