High Risk of Under-Grading and -Staging in Prostate Cancer Patients Eligible for Active Surveillance
High Risk of Under-Grading and -Staging in Prostate Cancer Patients Eligible for Active Surveillance
复制标题
DOI：
10.1371/journal.pone.0115537
复制
发表时间：
2015-02-06
期刊：
影响因子：
3.7
通讯作者：
Bektic, Jasmin
中科院分区：
文献类型：
--
作者：
Heidegger, Isabel;Skradski, Viktor;Bektic, Jasmin
背景主动监测（AS）越来越多地提供给低风险前列腺癌患者。本研究的目的是评估肿瘤分级和分期不足的风险，以确定AS的合格性。此外，我们分析了可能的生物标志物，以预测更不利的最终肿瘤组织学。方法197例接受根治性膀胱癌切除术（RPE），但符合EAU（欧洲泌尿外科协会）标准的AS（PSA）患者，
BackgroundActive surveillance (AS) is increasingly offered to patients with low risk prostate cancer. The present study was conducted to evaluate the risk of tumor under-grading and -staging for AS eligibility. Moreover, we analyzed possible biomarkers for predicting more unfavorable final tumor histology.Methods197 patients who underwent radical prostatectomy (RPE) but would have met the EAU (European Association of Urology) criteria for AS (PSA