Two new cytosporones from the culture of endophytic Phomopsis sp.
Two new cytosporones from the culture of endophytic Phomopsis sp.
复制标题
来自内生拟茎点霉培养物的两种新细胞孢子素。
DOI：
10.1007/s10600-013-0433-3
复制
发表时间：
2013-01-01
影响因子：
0.8
通讯作者：
Tan, R. X.
中科院分区：
文献类型：
--
作者：
Wu, Q.;Guo, Y.;Tan, R. X.
Two new octaketides, cytosporones T (1) and U (2), together with ten known metabolites including cytosporones A, B, C, M, and N, pestalotiopsones A, B, and F, and aspergillides A and C, were obtained from the culture of Phomopsis sp. IFB-ZS1-S4 habituating inside the healthy stem of Scaevola hainanensis Hance. The structures were unambiguously assigned by a combination of spectroscopic analyses. In vitro neuraminidase inhibitory bioassays of all compounds showed that aspergillide C and pestalotiopsone F were moderately active with IC50 values of 5.59 ± 0.44 and 9.90 ± 0.42 μM, respectively.
