Neural activation to upright and inverted faces in infants measured by near infrared spectroscopy
Neural activation to upright and inverted faces in infants measured by near infrared spectroscopy
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DOI：
10.1016/j.neuroimage.2006.08.013
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发表时间：
2007-01-01
期刊：
影响因子：
5.7
通讯作者：
Kakigi, Ryusuke
中科院分区：
文献类型：
--
作者：
Otsuka, Yumiko;Nakato, Emi;Kakigi, Ryusuke
本研究使用近红外光谱（NIRS）检测婴儿对正脸和倒脸的大脑活动，该技术可以无创记录大脑血流动力学的变化。MRS对婴儿的记录特别有用，因为即使在婴儿醒着的时候也可以进行记录，而不需要固定他们的身体和大脑。为了这个目的，我们使用了新开发的磁共振传感器探针来记录婴儿。我们测量了10个5-8个月大的婴儿在看直立和倒立的脸时大脑左外侧和右外侧区域的氧合变化。结果总结如下：(1)直立面部时，右侧区域的血红蛋白（oxyHb）和总血红蛋白（total- hb）浓度显著升高；(2)直立和倒立面部时右侧区域的总血红蛋白（total- hb）浓度差异显著；(3)颞区血流动力学变化最大，可能在两个半球的颞上沟（STS）。(4)右半球似乎对识别直立的面孔更重要。这是第一个用血流动力学方法证明婴儿脑内脸倒置效应存在半球间差异的证据。(c) 2006爱思唯尔公司版权所有。
The present study examined infants' brain activity in response to upright and inverted faces using near infrared spectroscopy (NIRS), which can non-invasively record hemodynamic changes of the brain. MRS is particularly useful for recording in infants, since recordings can be made, even while the infants are awake, without fixing their body and brain. For this objective, we used newly developed sensor probes of MRS for recording in infants. We measured changes in cerebral oxygenation in 10 5-8-month-olds' left and right lateral areas while they were looking at upright and inverted faces. The results are summarized as follows: (1) the concentration of oxyhemoglobin (oxyHb) and total hemoglobin (total-Hb) increased significantly in the right lateral area during the upright face condition, (2) the concentration of total-Hb in the right lateral area differed significantly between the upright and inverted conditions, (3) hemodynamic changes were maximal in the temporal region, probably in the superior temporal sulcus (STS) in both hemispheres, and (4) the right hemisphere seems to be more important for recognizing upright faces. This is the first evidence showing that there is an inter-hemispheric difference on the effect of face inversion in the infant brain using a hemodynamic method. (c) 2006 Elsevier Inc. All rights reserved.