DNA-templated assembly and electrode attachment of a conducting silver wire
DNA-templated assembly and electrode attachment of a conducting silver wire
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DOI：
10.1038/35826
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发表时间：
1998-02-19
期刊：
影响因子：
64.8
通讯作者：
Ben-Yoseph, G
中科院分区：
文献类型：
--
作者：
Braun, E;Eichen, Y;Ben-Yoseph, G
最近在纳米电子学领域的研究集中在两个基本问题上：小型器件的工作原理，以及导致它们实现并最终集成到有用电路中的方案。分子(1)到亚微米(2)量子点和碳纳米管中的电输运（3-5）的实验研究证实了理论预测（6-8），即随着器件尺寸的减小，充电效应的作用越来越大。然而，从这种设备构建纳米级电路仍然存在问题，主要是由于实现元件间布线和宏观电极的电接口的困难。利用分子识别过程和分子自组装成超分子结构（9,10）可能有助于克服这些困难。在这种情况下，DNA具有适当的分子识别（11）和机械特性（12-16），但糟糕的电气特性阻碍了它在电路中的直接使用。在这里，我们描述了一个两步程序，可以允许应用DNA tc，构建功能电路。在我们的方案中，DNA分子与表面结合的寡核苷酸杂交首先用于将其拉伸到两个金电极之间；然后将DNA分子用作12 μ m长，100 nm宽的导电银线矢量生长的模板。该实验证实，DNA的识别能力可以用于功能性电线的靶向连接。
Recent research in the field of nanometre-scale electronics has focused on two fundamental issues: the operating principles of small-scale devices, and schemes that lead to their realization and eventual integration into useful circuits, Experimental studies on molecular(1) to submicrometre(2) quantum dots and on the electrical transport in carbon nanotubes(3-5) have confirmed theoretical predictions(6-8) of an increasing role for charging effects as the device size diminishes. Nevertheless, the construction of nanometre-scale circuits from such devices remains problematic, largely owing to the difficulties of achieving inter-element wiring and electrical interfacing to macroscopic electrodes. The use of molecular recognition processes and the self-assembly of molecules into supramolecular structures(9,10) might help overcome these difficulties. In this context, DNA has the appropriate molecular-recognition(11) and mechanical(12-16) properties, but poor electrical characteristics prevent its direct use in electrical circuits. Here we describe a two-step procedure that may allow the application of DNA tc, the construction of functional circuits, In our scheme, hybridization of the DNA molecule with surface-bound oligonucleotides is first used to stretch it between two gold electrodes; the DNA molecule is then used as a template for the vectorial growth of a 12 mu m long, 100 nm wide conductive silver wire. The experiment confirms that the recognition capabilities of DNA can be exploited for the targeted attachment of functional wires.