Prevention of acute respiratory distress syndrome.
Prevention of acute respiratory distress syndrome.
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DOI：
10.1097/mcc.0000000000000174
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发表时间：
2015-02
影响因子：
3.3
通讯作者：
Gajic O
中科院分区：
文献类型：
--
作者：
Festic E;Kor DJ;Gajic O
急性呼吸窘迫综合征（ARDS）患者缺乏有效的治疗干预措施，再加上对危重患者及时实施有效治疗的重要性的大量证据，导致了最近ARDS研究的转变。越来越多的努力是为了及早发现有危险的病人，目的是在完全确定的综合症发展之前进行预防和早期治疗。这篇综述的重点是在他们的医疗保健遇到没有这种情况的患者的ARDS预防。在这篇综述文章中提出的主要主题类别包括：早期识别有发生ARDS风险的患者，优化护理服务及其对ARDS发病率的影响，ARDS的药物预防，术后ARDS的预防，以及ARDS预防研究的挑战和机遇。最近临床护理的改善与医院获得性ARDS发病率的降低有关。尽管最初面临挑战，但随着一些关于ARDS预防的随机对照试验已经完成或正在进行中，预防ARDS的研究已经变得越来越可行。
The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to the critically ill patients have resulted in a recent shift in ARDS research. Increasingly, efforts are being directed towards early identification of patients at risk with a goal of prevention and early treatment, prior to development of the fully established syndrome. The focus of this review is on the prevention of ARDS in patients without this condition at the time of their healthcare encounter. The primary thematic categories presented in this review article include: Early identification of patients at risk of developing ARDS, optimization of care delivery and its impact on the incidence of ARDS, pharmacological prevention of ARDS, prevention of postoperative ARDS, and challenges and opportunities with ARDS prevention studies. Recent improvements in clinical care delivery have been associated with a decrease in the incidence of hospital acquired ARDS. Despite the initial challenges, research in ARDS prevention has become increasingly feasible with several randomized controlled trials on ARDS prevention completed or on the way.