Trends in Ectopic Pregnancy Mortality in the United States 1980-2007
Trends in Ectopic Pregnancy Mortality in the United States 1980-2007
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DOI：
10.1097/aog.0b013e3182113c10
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发表时间：
2011-04-01
影响因子：
7.2
通讯作者：
Callaghan, William M.
中科院分区：
文献类型：
--
作者：
Creanga, Andreea A.;Shapiro-Mendoza, Carrie K.;Callaghan, William M.
目的：估计异位妊娠死亡率的趋势，并检查最近住院的妇女死于异位妊娠的特点在美国，方法：我们使用1980-2007年国家出生和死亡证明数据计算异位妊娠死亡率（每10万活产婴儿死亡）的整体和分层的母亲年龄和种族。我们对趋势进行了非参数检验，以评估异位妊娠死亡率随时间的变化，并计算了2013-2017年的预计死亡率。异位妊娠死亡的住院妇女中确定从1998 - 2007年全国住院Sample data.RESULTS：在1980年和2007年之间，876例死亡归因于异位妊娠。宫外孕死亡率在1980-1984年和2003-2007年期间下降了56.6%，从每100 000例活产死亡1.15人降至0.50人;按照目前的平均年下降率，到2013-2017年，这一比率将进一步下降28.5%，降至每100 000例活产死亡0.36人。2003-2007年期间，非裔美国人的异位妊娠死亡率是白人的6.8倍，35岁以上的妇女是25岁以下妇女的3.5倍。在1998年至2007年期间住院的76名死亡妇女中，70.5%是输卵管妊娠; 80.6%的病例进行了输卵管切除术。过度出血，休克，或肾功能衰竭伴随67.4%的异位妊娠死亡住院women.CONCLUSION：尽管异位妊娠死亡率显着下降，自20世纪80年代以来，年龄差异，特别是种族差异，持续存在。确保及时诊断和管理异位妊娠的战略可以进一步降低相关死亡率以及年龄和种族死亡率差距。（Obstet Gynecol 2011;117：837-43）DOI：10.1097/AOG.0b013e3182113c10
OBJECTIVE: To estimate trends in ectopic pregnancy mortality and examine characteristics of recently hospitalized women who died as a result of ectopic pregnancy in the United States.METHODS: We used 1980-2007 national birth and death certificate data to calculate ectopic pregnancy mortality ratios (deaths per 100,000 live births) overall and stratified by maternal age and race. We performed nonparametric tests for trend to assess changes in ectopic pregnancy mortality over time and calculated projected mortality ratios for 2013-2017. Ectopic pregnancy deaths among hospitalized women were identified from 19982007 Nationwide Inpatient Sample data.RESULTS: Between 1980 and 2007, 876 deaths were attributed to ectopic pregnancy. The ectopic pregnancy mortality ratio declined by 56.6%, from 1.15 to 0.50 deaths per 100,000 live births between 1980-1984 and 2003-2007; at the current average annual rate of decline, this ratio will further decrease by 28.5% to 0.36 ectopic pregnancy deaths per 100,000 live births by 2013-2017. The ectopic pregnancy mortality ratio was 6.8 times higher for African Americans than whites and 3.5 times higher for women older than 35 years than those younger than 25 years during 2003-2007. Of the 76 deaths among women hospitalized between 1998 and 2007, 70.5% were tubal pregnancies; salpingectomy was performed in 80.6% of cases. Excessive hemorrhage, shock, or renal failure accompanied 67.4% of ectopic pregnancy deaths among hospitalized women.CONCLUSION: Despite a significant decline in ectopic pregnancy mortality since the 1980s, age disparities, and especially racial disparities, persist. Strategies to ensure timely diagnosis and management of ectopic pregnancies can further reduce related mortality and age and race mortality gaps. (Obstet Gynecol 2011;117:837-43) DOI: 10.1097/AOG.0b013e3182113c10