Thyrotropin releasing factor: a putative CNS regulator of the autonomic nervous system.
Thyrotropin releasing factor: a putative CNS regulator of the autonomic nervous system.
复制标题
促甲状腺素释放因子：一种假定的自主神经系统中枢神经系统调节剂。
DOI：
10.1016/0024-3205(81)90350-7
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发表时间：
1981
期刊：
影响因子：
6.1
通讯作者：
M. Brown
中科院分区：
文献类型：
--
作者：
M. Brown
甲状腺激素释放因子(TRF)与大脑一起作用，提高血浆中肾上腺素和去甲肾上腺素的水平。与其他增加血浆肾上腺素水平的中枢神经系统刺激不同，TRF刺激的肾上腺素分泌不受生长抑素相关肽的抑制。与TRF引起的血浆儿茶酚胺增加相关的是血浆胰高血糖素和血糖的升高，这一效应可以通过肾上腺切除来防止。
Thyrotopin releasing factor (TRF) acts with the brain to elevate plasma levels of epinephrine and norepinephrine. In contrast to other CNS stimuli which increase plasma epinephrine levels, epinephrine secretion stimulated by TRF is not inhibited by peptides related to somatostatin. Associated with the TRF induced increase in plasma catecholamines is an elevation of plasma glucagon and glucose, effects which are prevented by adrenalectomy.