International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology
International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology
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DOI：
10.1016/j.jaci.2016.12.966
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发表时间：
2017-04-01
影响因子：
14.2
通讯作者：
Greenhawt, Matthew
中科院分区：
文献类型：
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作者：
Nowak-Wegrzyn, Anna;Chehade, Mirna;Greenhawt, Matthew
食物蛋白诱导的小肠结肠炎（FPIES）是一种非ige细胞介导的食物过敏，可能很严重并导致休克。尽管潜在的严重反应，但对FPIES的认识很低；缺乏提供病理生理学、诊断和管理方面的高质量研究；临床结果也不确定。这份共识文件是由美国过敏、哮喘和免疫学学会食品不良反应委员会和国际FPIES协会倡导小组召集的一个国际工作组所做工作的结果。这是第一个以证据为基础的国际指南，旨在改善FPIES患者的诊断和管理。研究该病的患病率、病理生理学、诊断标志物和未来的治疗方法对于改善对非典型ies患者的护理是必要的。这些指南将随着获得更多证据而定期更新。
Food protein-induced enterocolitis (FPIES) is a non-IgE cell-mediated food allergy that can be severe and lead to shock. Despite the potential seriousness of reactions, awareness of FPIES is low; high-quality studies providing insight into the pathophysiology, diagnosis, and management are lacking; and clinical outcomes are poorly established. This consensus document is the result of work done by an international workgroup convened through the Adverse Reactions to Foods Committee of the American Academy of Allergy, Asthma & Immunology and the International FPIES Association advocacy group. These are the first international evidence-based guidelines to improve the diagnosis and management of patients with FPIES. Research on prevalence, pathophysiology, diagnostic markers, and future treatments is necessary to improve the care of patients with FPIES. These guidelines will be updated periodically as more evidence becomes available.