ADENOVIRUS SEROTYPES ISOLATED FROM OCULAR INFECTIONS IN LONDON
ADENOVIRUS SEROTYPES ISOLATED FROM OCULAR INFECTIONS IN LONDON
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DOI：
10.1136/bjo.67.2.111
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发表时间：
1983-01-01
影响因子：
4.1
通讯作者：
MCSWIGGAN, DA
中科院分区：
文献类型：
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作者：
DAROUGAR, S;WALPITA, P;MCSWIGGAN, DA
在1973-87年期间，从穆尔菲尔德眼科医院就诊的患者的眼睛中分离出700例腺病毒。其中，678人通过中和试验进行了血清分型。鉴定出21种不同的血清型。血清型3、7、10占分离株的68%，4、8、15(15/29)、19占25%，其他14个血清型占7%。观察到由腺病毒3、4、7、10和15(15/29)引起的眼部感染的社区暴发。腺病毒3、7和10的暴发似乎持续了2年或更长时间，而4和15(15/29)的暴发被限制在一年或更短的时间内。还记录了由腺病毒8和19在医院爆发的情况。在这21种型腺病毒中，有18种是在7804例患者的非眼部(主要是呼吸道)分离到的。腺病毒1、2、3、5、6在眼部和非眼部的分布密切相关。腺病毒血清型4、8、10、15(15/29)和19型之间没有观察到这种关联。
During the period 1973-8 700 adenoviruses were isolated from the eyes of patients presenting at Moorfields Eye Hospital. Of these, 678 were serotyped by a neutralisation test. Twenty-one different serotypes were identified. Serotype 3, 7, and 10 accounted for 68% of the isolates, 4, 8, 15 (15/29), and 19 for 25%, and the other 14 serotypes for 7%. Community outbreaks of ocular infections by adenovirus 3, 4, 7, 10, and 15 (15/29) were observed. Outbreaks with adenovirus 3, 7, and 10 appeared to continue for 2 years or more, whereas outbreaks with 4 and 15 (15/29) were restricted to one year or less. Hospital outbreaks by adenovirus 8 and 19 were also recorded. During the same period 18 of these 21 adenovirus serotypes were isolated from the nonocular sites (mainly respiratory tract) in 7804 cases. There was a close association in the distribution of adenovirus 1, 2, 3, 5, and 6 in the ocular and nonocular sites. No such association was observed for adenovirus serotypes 4, 8, 10, 15 (15/29), and 19.