Identifying seizure clusters in patients with epilepsy
Identifying seizure clusters in patients with epilepsy
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DOI：
10.1212/01.wnl.0000180685.84547.7f
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发表时间：
2005-10-25
期刊：
影响因子：
9.9
通讯作者：
Shinnar, S
中科院分区：
文献类型：
--
作者：
Haut, SR;Lipton, RB;Shinnar, S
临床医生经常遇到神经系统发作呈聚集性的患者。在日常日记研究中，作者探讨了聚类是否是癫痫的真实现象并且可以在临床环境中识别。近一半的受试者在 24 小时内经历过至少 1 次癫痫发作或 3 次以上癫痫发作； 20% 还满足统计聚类标准。利用聚类的临床定义应识别所有癫痫聚类，并且可以通过日记数据确定假阳性。
Clinicians often encounter patients whose neurologic attacks appear to cluster. In a daily diary study, the authors explored whether clustering is a true phenomenon in epilepsy and can be identified in the clinical setting. Nearly half the subjects experienced at least one episode of three or more seizures in 24 hours; 20% also met a statistical clustering criterion. Utilizing the clinical definition of clustering should identify all seizure clusterers, and false positives can be determined with diary data.