Placental Malaria and Lack of Prenatal Care in an Area of Unstable Malaria Transmission in Eastern Sudan
Placental Malaria and Lack of Prenatal Care in an Area of Unstable Malaria Transmission in Eastern Sudan
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DOI：
10.1645/ge-1912.1
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发表时间：
2009-06-01
影响因子：
1.3
通讯作者：
Ryan, C. Anthony
中科院分区：
文献类型：
--
作者：
Adam, Ishag;Adam, Gamal K.;Ryan, C. Anthony
在苏丹东部的Gadarif医院进行了一项横断面研究，以确定胎盘疟疾的患病率，并评估其危险因素。236名分娩妇女参加了这项研究。通过问卷调查收集社会人口特征。测量母体血红蛋白，确定ABO血型，并进行疟疾胎盘组织学检查。还记录了新生儿的出生体重。平均（SD）母亲年龄为25.5（6.0）岁，平均（SD）血红蛋白为9.8（0.9）g/dl。胎盘组织学显示13例（5.5%）急性疟疾感染和5例（2.1%）慢性感染; 28例（11.9%）胎盘显示既往感染，190例（80.5%）未显示感染。缺乏产前护理与胎盘感染显著相关（OR = 12.0，95%CI = 2.3-16.2; P = 0.003）。胎盘疟疾感染与母亲年龄、产次和血型之间无显著相关性。这些妊娠结局中有32例（13.5%）导致低出生体重婴儿。然而，胎盘疟疾与低出生体重之间没有显著相关性（OR = 2.0，95%CI = 0.4-4.1; P = 0.1）。因此，胎盘疟疾感染影响到苏丹东部这一地区的孕妇，无论她们的年龄或产次如何。应鼓励产前保健，以减少该地区的疟疾。需要更多关于疟疾和怀孕的研究。
A cross-sectional Study was conducted in Gadarif Hospital in eastern Sudan to determine the prevalence, and evaluate the risk factors, of placental malaria. Two hundred and thirty-six delivering women were enrolled in the study. Socio-demographic characteristics were gathered through questionnaires. Maternal hemoglobin was measured, ABO blood groups were determined, and placental histological examinations for malaria were performed. The birth weight of the newborn was also recorded. The mean (SD) maternal age was 25.5 (6.0) yr and the mean (SD) hemoglobin was 9.8 (0.9) g/dl. Placental histology showed acute malaria infections in 13 (5.5%) and chronic infections in 5 (2.1%) women; 28 (11.9%) of the placentas revealed past infection and 190 (80.5%) indicated no infection. Lack of prenatal care was significantly associated with placental infections (OR = 12.0, 95% CI = 2.3-16.2; P = 0.003). There was no significant association between placental malaria infections and maternal age, parity, and blood group. Thirty-two (13.5%) of these pregnancy Outcomes resulted in low birth-weight babies. There was, however, no significant association between placental malaria and low birth weight (OR = 2.0, 95% CI = 0.4-4.1; P = 0.1). Thus, placental malaria infections affect pregnant women ill this area of eastern Sudan regardless of their age or parity. Prenatal care should be encouraged to reduce malaria in the area. Much more research regarding malaria and pregnancy is needed.