Drug and alcohol use among people living with HIV in care in the United States by geographic region.

Drug and alcohol use among people living with HIV in care in the United States by geographic region.
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DOI:
10.1080/09540121.2021.1874274
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发表时间:
2021-12
影响因子:
1.7
通讯作者:
Delaney, Joseph A. C.
Delaney, Joseph A. C.
中科院分区:
医学4区
文献类型:
--
作者:
Crane, Heidi M.;Nance, Robin M.;Whitney, Bridget M.;Ruderman, Stephanie;Tsui, Judith I.;Chander, Geetanjali;McCaul, Mary E.;Lau, Bryan;Mayer, Kenneth H.;Batey, D. Scott;Safren, Steven A.;Moore, Richard D.;Eron, Joseph J.;Napravnik, Sonia;Mathews, W. Chris;Fredericksen, Rob J.;Hahn, Andrew W.;Mugavero, Michael J.;Lober, William B.;Saag, Michael S.;Kitahata, Mari M.;Delaney, Joseph A. C.

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美国的药物使用因地理区域而异。阿片类药物处方实践和大麻,海洛因和甲基苯丙胺的可用性在各地区的发展不同。我们检查了2017-2019年7个地点的艾滋病毒感染者(PLWH)自我报告的物质使用情况,以了解当前的区域物质使用模式。我们计算了美国人口普查局地理区域报告当前药物使用和风险以及酗酒的PLWH的百分比和标准化百分比,并在调整后的logistic回归分析中检查了相关性。在7,686名PLWH中,大麻使用是最普遍的药物(30%),其次是甲基苯丙胺/晶体(8%),可卡因/快克(7%)和非法阿片类药物(3%)。三分之一报告酗酒(32%)。大麻(24-41%)和甲基苯丙胺/晶体(2-15%)的当前使用百分比存在地区差异,西部和东北部使用更多,酗酒(26-40%)。在调整后的分析中,与西部的PLWH相比,中西部的PLWH使用甲基苯丙胺/晶体(aOR:0.13;0.06-0.25)或非法阿片类药物(aOR:0.16;0.05-0.53)的可能性显著降低,东北部的PLWH更可能使用可卡因/快克(aOR:1.59;1.16-2.17)。随着政策的不断发展,了解当今时代物质使用模式的差异,将使艾滋病毒携带者在临床环境中采取更有针对性的干预措施。
Substance use in the U.S. varies by geographic region. Opioid prescribing practices and marijuana, heroin, and methamphetamine availability are evolving differently across regions. We examined self-reported substance use among people living with HIV (PLWH) in care at seven sites from 2017-2019 to understand current regional substance use patterns. We calculated the percentage and standardized percentage of PLWH reporting current drug use and at-risk and binge alcohol use by U.S. Census Bureau geographic region and examined associations in adjusted logistic regression analyses. Among 7,686 PLWH, marijuana use was the most prevalent drug (30%), followed by methamphetamine/crystal (8%), cocaine/crack (7%), and illicit opioids (3%). One-third reported binge alcohol use (32%). Differences in percent of current use by region were seen for marijuana (24-41%) and methamphetamine/crystal (2-15%), with more use in the West and Northeast, and binge alcohol use (26-40%). In adjusted analyses, PLWH in the Midwest were significantly less likely to use methamphetamine/crystal (aOR: 0.13;0.06-0.25) or illicit opioids (aOR:0.16;0.05-0.53), and PLWH in the Northeast were more likely to use cocaine/crack (aOR:1.59;1.16-2.17), compared to PLWH in the West. Understanding differences in substance use patterns in the current era, as policies continue to evolve, will enable more targeted interventions in clinical settings among PLWH.
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