Mitochondrial nitric oxide synthase: A ubiquitous regulator of oxidative phosphorylation?
Mitochondrial nitric oxide synthase: A ubiquitous regulator of oxidative phosphorylation?
复制标题
DOI：
10.1006/bbrc.1996.0008
复制
发表时间：
1996-01-05
影响因子：
3.1
通讯作者：
Clark, JB
中科院分区：
文献类型：
--
作者：
Bates, TE;Loesch, A;Clark, JB
在这篇文章中，我们证明了从心脏，骨骼肌和肾脏分离的线粒体中的一氧化氮合酶的免疫细胞化学定位，使用针对内皮形式的一氧化氮合酶的单克隆抗体。可能性，nitrically位于一氧化氮合酶是一个普遍存在的调节线粒体氧化磷酸化在哺乳动物细胞进行了讨论。(C)出版社：Academic Press，Inc.
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed. (C) 1996 Academic Press, Inc.