Primary intestinal T-cell lymphoma resembling lymphomatous polyposis: report of a case
Primary intestinal T-cell lymphoma resembling lymphomatous polyposis: report of a case
复制标题
类似淋巴瘤性息肉病的原发性肠道T细胞淋巴瘤一例报告
DOI：
10.1007/s004280000270
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发表时间：
2000
期刊：
影响因子：
3.5
通讯作者：
O. Tokunaga
中科院分区：
文献类型：
--
作者：
A. Ogawa;N. Fukushima;T. Satoh;M. Kishikawa;K. Miyazaki;O. Tokunaga
We report an interesting case of primary intestinal T-cell lymphoma (ITL) resembling lymphomatous polyposis (LP) in a 24-year-old man. The neoplasm macroscopically showed numerous small polyps throughout the colon and microscopically showed diffuse proliferation of small-sized tumor cells with occasionally cleaved or irregularly shaped nuclei. The tumor cells were immunohistochemically positive for CD3, CD8, TIA-1, and CD56, and a polymerase chain reaction study showed a single band, indicating monoclonal rearrangement of the T-cell receptor β gene. The phenotypic features in the current case are consistent with those of ITL derived from cytotoxic CD56+CD8+ intraepithelial lymphocytes. This is the second documented case of primary ITL with a morphologic pattern of LP.
