Autonomic nervous activity changes in relation to the reporting of subjective symptoms among male workers in an information service company

Autonomic nervous activity changes in relation to the reporting of subjective symptoms among male workers in an information service company
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DOI:
10.1007/s00420-005-0062-7
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发表时间:
2006-05-01
影响因子:
3
通讯作者:
Yano, E
Yano, E
中科院分区:
医学3区
文献类型:
--
作者:
Karita, K;Nakao, M;Yano, E

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目的:本研究的目的是通过心率变异性(HRV)功率谱分析来阐明主要主观症状与自主神经系统功能之间的关系。研究方法:对日本某信息服务公司413名19-45岁男性员工进行了短期心率变异性检查,并在每年体检时进行了主观症状和生化指标的问卷调查。结果:患者最常见的主观症状是感觉迟钝(>= 10%),其次是乏力、背痛、腹泻、睡眠障碍和烦躁。有上述6种症状者的高频(HF 0.15-0.40 Hz)HRV及心电图R-R间期(CVrr)变异系数均低于无症状者。通过多元回归分析,这两个参数与报告的任何六种症状呈负相关,控制了年龄(HF和CVrr)和血浆皮质醇水平(HF)的显着影响。结论:主观症状的报告是副交感神经张力降低的良好预测指标之一。
Objectives: The objective of the study was to clarify the relationship between major subjective symptoms and autonomic nervous system function by power spectral analysis of heart rate variability (HRV). Methods: Short-term HRV was examined for 413 male workers in a Japanese information service company aged 19-45 years, and questionnaire survey on subjective symptoms and biochemical measurements were conducted at annual health checkup. Results: The most prevalent subjective symptom (>= 10%) was dullness, followed by fatigue, backache, diarrhea, sleep disorder, and irritation. HRV in high frequency (HF 0.15-0.40 Hz) bands and the coefficient of variance in the electrocardiographic R-R interval (CVrr) were lower in the subjects with any of these six symptoms than in those without the symptoms. Both parameters were negatively associated with the reporting of any of the six symptoms by multiple regression analyses, controlling for the significant effects of age (HF and CVrr) and plasma cortisol levels (HF). Conclusion: It was suggested that the reporting of the subjective symptoms is one of good predictors for reduced parasympathetic tones.