A novel assay for quantifying the number of plasmids encapsulated by polymer nanoparticles.
A novel assay for quantifying the number of plasmids encapsulated by polymer nanoparticles.
复制标题
DOI:
10.1002/smll.201101718
复制
发表时间:
2012-02-06
期刊:
影响因子:
13.3
通讯作者:
Green, Jordan J.
中科院分区:
文献类型:
--
作者:
Bhise, Nupura S.;Shmueli, Ron B.;Gonzalez, Jose;Green, Jordan J.
Polymeric nanoparticles are promising for gene therapy and stem cell reprogramming using non-viral vectors. A novel assay utilizing nanoparticle tracking analysis (left) is developed here to easily quantify the number of plasmids within polymeric nanoparticles while in aqueous solution. Particles effective at co-transfecting primary human fibroblasts (right) are ~100 nm in diameter and contain ~100 plasmids per particle.
登录
查看更多内容
DOI:
10.1016/j.bbagen.2004.02.004
发表时间:
2004-04-07
影响因子:
3
作者:
Collins, L;Kaszuba, M;Fabre, JW
通讯作者:
Fabre, JW
影响因子:
14.9
作者:
Kreiss, P;Cameron, B;Pitard, B
通讯作者:
Pitard, B
影响因子:
64.8
作者:
Park, In-Hyun;Zhao, Rui;Daley, George Q.
通讯作者:
Daley, George Q.
影响因子:
14
作者:
Bhise, Nupura S.;Gray, Ryan S.;Sunshine, Joel C.;Htet, Soe;Ewald, Andrew J.;Green, Jordan J.
通讯作者:
Green, Jordan J.
影响因子:
2.9
作者:
ARSCOTT, PG;LI, AZ;BLOOMFIELD, VA
通讯作者:
BLOOMFIELD, VA