Alcohol Consumption, Cardiovascular Risk Factors, and Mortality in Two Chicago Epidemiologic Studies
Alcohol Consumption, Cardiovascular Risk Factors, and Mortality in Two Chicago Epidemiologic Studies
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芝加哥两项流行病学研究中的饮酒量、心血管危险因素和死亡率
作者：
A. Dyer;J. Stamler;O. Paul;D. Berkson;M. Lepper;Harlley Mckean;R. Shekelle;H. Lindberg;D. Garside
对芝加哥人民天然气公司1,233名年龄在40-59岁的白人男性员工的基线饮酒问题与心血管风险因素之间的关联进行了多因素分析，结果显示，38名问题饮酒者的血压和吸烟量显著高于其他人，相对体重显著低于其他人。对芝加哥西部电气公司霍桑工厂的1899名白人男性员工进行的类似分析显示，117名男性每天饮酒5杯或更多，血压和吸烟水平明显高于其他人。大量饮酒者与其他饮酒者之间的血清胆固醇水平无显著差异。天然气公司的问题饮酒者因各种原因、心血管疾病、冠心病和猝死而15年的死亡率明显更高。这些差异不能完全用他们的血压、吸烟和相对体重状况来解释。西部电力公司的酗酒者增加了所有原因和非心血管原因的10年死亡率。
Multivariate analysis of the association at baseline between problem drinking and cardiovascular risk factors among 1,233 white male employees of the Chicago Peoples Gas Company age 40-59 showed the 38 problem drinkers with significantly higher blood pressures and cigarette consumption and significantly lower relative weights than the others. Similar analyses among 1,899 white male employees of the Hawthorne Works of the Western Electric Company in Chicago age 40-55 showed the 117 men consuming 5 or more drinks per day with significantly higher blood pressures and cigarette use than the others. No significant differences were recorded between heavy drinkers and the others in serum cholesterol level. The gas company problem drinkers had significantly higher 15- year mortality rates from all causes, cardiovascular diseases, coronary heart disease, and sudden death. These differences could not be entirely explained by their blood pressure, smoking, and relative weight status. The Western Electric heavy drinkers had increased 10-year mortality rates both for all causes and noncardiovascular causes.