Latent class and factor analysis of DSM-IV ADHD: A twin study of female adolescents

Latent class and factor analysis of DSM-IV ADHD: A twin study of female adolescents
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DOI:
10.1097/00004583-199808000-00015
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发表时间:
1998-08-01
影响因子:
13.3
通讯作者:
Todd, RD
Todd, RD
中科院分区:
医学1区
文献类型:
--
作者:
Hudziak, JJ;Heath, AC;Todd, RD

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目的:为了验证女性注意力缺陷多动障碍(ADHD)的现行DSM-IV标准,并确定症状是连续分布的还是分类离散的,作者对来自大量青少年女性双胞胎(1,629对)的ADHD症状数据进行了因子和潜在类别分析。方法:通过电话对1,629对父母中的至少一人进行了DSM-IV ADHD的结构化诊断评估。对1,549对ADHD症状进行了潜在类别和因素分析。结果如下:潜在的类和因素分析是一致的存在单独的连续域的注意力不集中(ATT),多动-冲动(H-I),并结合ATT与H-I的问题。严重的潜伏类对应的主要是注意力不集中,主要是多动-冲动,和组合类型被确定与终生患病率估计分别为4.0%,2.2%和3.7%。严重ATT类的成员预测学术问题,家庭问题,并转介到医疗保健提供者。H-I和混合类的成员资格也预测了受损的社会关系。结论:这些结果表明,DSM-IV ADHD亚型可以被认为是存在于注意力不集中、多动-冲动的独立连续体上。和组合型问题。在任何三个严重的ADHD潜伏类的成员资格并不妨碍学术卓越,但ii,与不同类型的损害和寻求医疗保健的行为。这些数据在诊断、分类、治疗和研究领域都有意义。
Objective: In an attempt to validate the current DSM-IV criteria for attention-deficit/hyperactivity disorder (ADHD) in females and to determine whether symptoms are continuously distributed or categorically discrete, the authors performed factor and latent class analysis on ADHD symptom data from a large general population of adolescent female twins (1,629 pairs). Method: A structured diagnostic assessment of DSM-IV ADHD was completed with at least one parent of 1,629 pairs by telephone. ADHD symptoms from 1,549 pairs were subjected to latent class and factor analysis. Results: Latent class and factor analyses were consistent with the presence of separate continuous domains of inattention (ATT), hyperactivity-impulsivity (H-I), and combined ATT with H-I problems. Severe latent classes corresponding to the predominantly inattentive, predominantly hyperactive-impulsive, and combined types were identified with lifetime prevalence estimates of 4.0%, 2.2%, and 3.7%, respectively. Membership in the severe ATT class predicted academic problems, family problems, and referral to health care providers. Membership in the H-I and combined classes also predicted impaired social relationships. Conclusions: These results suggest that DSM-IV ADHD subtypes can be thought of as existing on separate continua of inattention, hyperactivity-impulsivity. and combined type problems. Membership in any of the three severe ADHD latent classes did not preclude academic excellence, but ii, was associated with different types of impairment and health care-seeking behavior. These data have implications in the areas of diagnosis, classification, treatment, and research.