Unmyelinated tactile afferents have opposite effects on insular and somatosensory cortical processing
Unmyelinated tactile afferents have opposite effects on insular and somatosensory cortical processing
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DOI：
10.1016/j.neulet.2008.03.015
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发表时间：
2008-05-09
影响因子：
2.5
通讯作者：
Bushnell, M. Catherine
中科院分区：
文献类型：
--
作者：
Olausson, Hakan W.;Cole, Jonathan;Bushnell, M. Catherine
先前的功能磁共振成像（fMRI）研究的A-β deafferented主题（GL）表明，刺激触觉C传入（CT）激活岛叶皮层，而没有激活被认为是在体感皮层。心理物理学研究表明，CT传入有助于情感，但不歧视方面的触觉刺激。我们现在已经检查了皮层处理后，在第二个类似的去传入受试者（IW）的CT刺激，以及重新访问的数据从GL。IW的结果显示，与GL相似，CT刺激后后岛叶皮质的激活，因此加强了CT传入支持触摸情感方面的观点。此外，CT刺激引起显着的功能磁共振成像失活的躯体感觉皮层在这两个科目支持的概念，CT是不是一个系统的歧视触摸。(C)2008爱思唯尔爱尔兰有限公司保留所有权利。
A previous functional magnetic resonance imaging (fMRI) study of an A-beta deafferented subject (GL) showed that stimulation of tactile C afferents (CT) activates insular cortex whereas no activation was seen in somatosensory cortices. Psychophysical studies suggested that CT afferents contribute to affective but not to discriminative aspects of tactile stimulation. We have now examined cortical processing following CT stimulation in a second similarly deafferented subject (IW), as well as revisited the data from GL. The results in IW showed similar activation of posterior insular cortex following CT stimulation as in GL and so strengthen the view that CT afferents underpin emotional aspects of touch. In addition, CT stimulation evoked significant fMRI deactivation in somatosensory cortex in both subjects supporting the notion that CT is not a system for discriminative touch. (C) 2008 Elsevier Ireland Ltd. All rights reserved.